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The observed findings supported the recent work carried out following tramadol-treatment tramadol withdrawal journal tramadol hcl extended release dosage tramadol hcl with advil tramadol by Ahmed and Kurkar [14] and Abdellatief et al .
The authors revealed that tramadol-treatment led to a decrease of testosterone and total cholesterol and increased level of the the testicular levels of nitric oxide and lipid peroxidation, and decreased ultram the anti-oxidant enzymes activities significantly compared with the control group .
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Its administration led to disruption of ultram the spermatogenic cells from the membranes [21] .
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